The Lost Enzyme Project was created by the families of children diagnosed with Beta-mannosidosis in the United States in collaboration with the University of California Irvine Foundation, Kimonis Laboratory, and JCR Pharmaceuticals to create a novel enzyme replacement therapy. Our project, working through the University of California Irvine Foundation, has set a goal of raising $520,925.00 by August 1, 2025, to fund the development of a new treatment with JCR Pharmaceuticals. Donate via Bright to ensure you get the Company match (!) but, if you would like more information, please visit the UCI Health's project website at https://fundraise.givesmart.com/e/o2kg0g?vid=114x2x.